Lisa Harding, MD 

About Dr. Lisa Harding

Lisa Harding, MD has completed over 4,000 interventional procedures, including Electroconvulsive Therapy (ECT), Repetitive Transcranial Magnetic Stimulation (rTMS), Intranasal Esketamine (Spravato), and Intravenous Ketamine. She played a critical role in operationalizing Esketamine administration at Yale, ensuring compliance with Risk Evaluation and Mitigation Strategy (REMS) guidelines after its FDA approval in 2019.

Recognized as one of the top intervention psychiatrists in Connecticut, Dr. Harding is sought after locally, nationally, and internationally as an expert in her field. She has addressed audiences nationally and worldwide, including in Saudi Arabia, Singapore, Australia, Italy, Romania, Brazil, Mexico, Guyana, and St. Lucia. She has held leadership roles in the American Psychiatric Association (APA) and served as Vice President of the American Society of Ketamine Physicians, Psychotherapists & Practitioners.

Clinical Practice

At Mood Institute, we prioritize individualized care. Our services encompass:

Interventional Psychiatry (Spravato™, Ketamine, TMS).

Rapid relief options for treatment-resistant depression, administered under professional supervision.​

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Medication Management

Ongoing evaluation of medication effectiveness to ensure optimal outcomes.​

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Clinical Research and Innovation (Clinical and AI Driven Applications)

The study identifies eight crucial domains where AI improves clinical prediction, notably in diagnosis, prognosis, and personalized medicine.

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About Mood Institute

Mood Institute is a best-in-class psychiatric clinic specializing in advanced, cutting-edge treatments for depression and mood disorders, including Esketamine (Spravato™), Ketamine, TMS, and medication management. Known for its personalized, bilingual care, the clinic combines clinical excellence with innovative technology to support superior patient outcomes. It has been selected as a clinical trial site for a PCORI-funded study comparing IV ketamine to Esketamine and will host two additional Phase 3 trials over the next three years—solidifying its role as a national leader in treatment-resistant depression and interventional psychiatric research.